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KMID : 1059519950390090728
Journal of the Korean Chemical Society
1995 Volume.39 No. 9 p.728 ~ p.733
Synthesis of New 2-Amino-4-methylcyano-5-methylsulfonylpyrimidine Derivatives
Kim Jung-Hwan

Han Mun-Su
Kim Un-Ju
Abstract
The derivatives of 2-amino-4-methylcyano-5-methylsulfonylpyrimidine 6 containing chloro, methoxy, ethoxy, phenoxy, amino and anilino groups at 6-position on the pyrimidine ring were prepared from 2-amino-4-chloro-5-methylsulfonylpyrimidine derivatives 4 and tert-butylcyanoacetate. The derivatives of 2-amino-4-chloro-5-methylsulfonylpyrimidine 4 containing methoxy, ethoxy, isopropoxy, phenoxy, amino and anilino groups at 6-position on the pyrimidine ring were prepared from 2-amino-4,6-dichloro-5-methylsulfonylpyrimidine 3.
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